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雷尼替丁对胆石症病人术后外周血Th/Ts的逆转作用

PREVENTION OF ALTERATIONS IN T LYMPHOCYTESUBPOPULATIONS AFTER BILIARY SURGERYAND RANITIDINE TREATMENT
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摘要 本文选择了49例胆石症的手术病人作为研究对象,随机分成对照组和雷尼替丁治疗者,手术前后测定外周血T淋巴细胞亚群的变化。结果表明,对照组术后Th明显降低(P<0.05),治疗组Th下降不明显,雷尼替丁能明显增加术后Th/Ts的比值,提高细胞免疫力。本文还就雷尼替丁作用机理进行了讨论。 he levels of the circulating T lymphocyte subpopulations were measured in 49 patients withcholelithiasis during the biliary operation. These patients were randomly divided into two groups : groupl without ranitidine treatment and group 11 with ranitidine treatment. The results showed that theactivity of Th cells in group I was decreased significantly after operation (P<0. 05).There was noremarked change in group ll. Ranitidine can increase the ratio of Th/Ts and improve the immuno-suppressive state after biliary sutgery.
出处 《中国普通外科杂志》 CAS CSCD 1994年第1期24-25,28,共3页 China Journal of General Surgery
关键词 胆结石 雷尼替丁 T细胞亚群 Cholelithiasis Ranitidine T lymphocyte subpopulation.
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