甲硝唑或右旋糖酐腹腔灌注对术后腹腔粘连影响的实验研究

EXPERIMENTAL STUDY OF IMPACT ON POSTOPERATIVEABDOMINAL ADHESION WITH METRONIDAZOLE ORDEXTRAN INTQ ABDOMINAL CAVITY

用甲硝唑或右旋糖酐灌注腹腔，作术后腹腔粘连形成和腹腔粘连松解后粘连再形成的实验研究。结果表明：甲稍唑通过抗菌消炎作用具有显著预防腹腔粘连作用（Ｐ＜０．０５）。６％Ｄ７０具有显著预防术后腹腔粘连作用（Ｐ＜０．０５），６％Ｄ４０作用不可靠（一次Ｐ＜０．０５，三次Ｐ＞０．０５）。为腹腔内使用甲硝唑或右旋糖酐提供了实验依据。

xperimental studies in dogs showed that both Metronidazole and Dextranplayed an important role in the prevention of postoperative abdominal adhesionformation and reformation after surgical excision. The role of Metronidazole andDextran-70 was statistically significant while that of Dextran-40 was not. Thepresumable mechanisms of the results were discussed.