胎肝胎胰联合移植治疗NIDDM1例报告

FETAL LIVER AND PANCREAS COTRANSPLANTATION IN A TYPE I DIABETIE PATIENT

本文报道了胎肝胎胰联合移植及术后定期胎肝组织块移植治疗Ⅱ型糖尿病(NIDDM)的可行性,我们在1993年11月为一例NIDDM病人试行胎胰胎肝联合移植及术后定期胎肝组织块移植治疗,术后24天,停用胰岛素,已维持8月,血糖正常,基础胰岛素水平恢复正常。结果表明:胎肝胎胰联合移植不仅可纠正NIDDM的糖代谢紊乱,使基础胰岛素水平恢复正常,并可缓解和纠正原有的并发症。使患者获得治愈。

The paper investigated the possible therapeutic effect of fetal liver and pancreas contransplantation, followed postoperatively by periolic intraperitoneal injection of fetal liver tissue suspension in a patient with non-insulin dependent diabetes menitus (NIDDM). The administration of exogenous insulin was stappedbeginning from the 24 day postoperatively and during the 8 months of followup. Blood sugar level is normal and basal insulm level has returned to normal, thus indicating that combined fetal liver and pancreas transplantation can correct the glucose metabolic disorder, and restore the basal insulin level to normal with relief and correction of diabetic complications and may cure NIDDM.