成人重症肌无力与胸腺病变

Adult myasthenia gravis and thymus

本文研究分析了７７０例成人重症肌无力患者中有关胸腺的检测结果。１５６例共同接受血清柠檬酸提取物抗体（ＣＡＥ—Ａｂ）检测和纵隔ＣＴ检查，结果显示两者的相符率为８７．８％（１３７／１５６）；６２例术前ＣＴ和术后病理诊断的相符率为８５．８％（５３／６２）；８２例血清ＣＡＥ—Ａｂ与胸腺病理的相符率为８７．８％（７２／８２；７７例胸腺病理与ＭＧ临床Ｏｓｓｅｒｍａｎ分型研究说明ＭＧ伴发胸腺瘤患者中以ⅡＢ、Ⅲ、Ⅳ型为多，病情相对较重。文章对各种胸腺检查方法的优缺点进行了分析比较，强调综合考虑对胸腺摘除术前、术后准确评价胸腺改变的重要性。

In this article, 770 cases of myasthenia gravis (MG) patients were reviewed. Detection of the antibodies to citric acid extract (CAE-Ab) in the sera and the mediastinal CT were performed simul taneously in 156 patients, and the results were coincident with each other in 87.8% (137/156). The analysis of 62 cases indicated that mediastinal CT results were in correspondence with pathological examination results in 85.8% (53/62), as sera CAE -Ab and thymus pathology, the rate 87.8% (72/82).According to the modified classification of osserman,most patientS, of MG with thymoma were type ⅡB, Ⅲ and Ⅳ, whose conditions were more se vere. Comprehensive analysis of different examina tions of thymus in MG patients is emphasized in this article.