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抗结核治疗中出现肝损害的认识

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摘要 药物性肝损害(drug—induced liver injury)是指药物在治疗过程中肝脏由于药物的毒性损害或对药物的过敏反应所致的疾病,又称为药物性肝病。据报道,药物性肝损害占整个药物不良反应的10%-15%。临床上,引起药物性肝损害的药物种类繁多,其中最常见的当属抗结核药物。本文就抗结核治疗中出现肝损害的相关问题浅述如下。
作者 徐新献
出处 《世界今日医学杂志》 2005年第1期60-62,共3页 World JOurnal of Medicine Today
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  • 1Turktas H, Unsal M, Tulek N, et al. Hepatotoxicity of antituberculosis therapy (rifampicin, isoniazidand and pyrazinamide) or viral hepatitis.Tuber Lung Dis, 1994, 75: 58-60.
  • 2Jasmer RM, Daley CL. Rifampin and pyrazinamide for treatment of latent tuberculosis infection: is it safe? Am J Respir Crit Care Med,2003, 167: 809-810.
  • 3Kaplowitz N. Drug-induced liver disorders: implications for drug development and regulation. Drug Saf, 2001, 24: 483-490.
  • 4Kunimoto D, Warman A, Beckon A, et al. Severe hepatotoxicity associated with rifampin-pyrazinamide preventative therapy requiring transplantation in an individual at low risk for hepatotoxicity. Clin Infect Dis, 2003, 36: 158-161.
  • 5Castro KG, Jereb JA, Koppaka VR, et al. Fatal liver injury associated with rifampin-pyrazinamide treatment of latent tuberculosis infection. Chest, 2003, 123: 967.
  • 6Huang YS,Chern HD,Su WJ,et al.Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis.Hepatology,2002,35(4):883-839
  • 7Huang YS,Chern HD,Su WJ,et al.Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis.Hepatology,2003,37(4):924-930
  • 8Sharma SK,Balamurugan A,Saha PK,et al.Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment.Am J Respir Crit Care Med,2002,166(7):916-919
  • 9Yee D,Valiquette C,Pelletier M,et al.Incidence of serious side from first-line antituberculosis drugs among patients treated for active tuberculosis.Am J Respir Crit Care Med,2003,167(11):1472-1477
  • 10Tiwari VK.Alcoholic hepatic impairment complicating treatment with hepatotoxic antituberculosis drugs.J Indian Med Assoc,1996,94(9):347-348

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