冬虫夏草多糖脂质体口服液的质量标准

Quality standards for the Cordyceps sinensis Sacc polysaccharide liposomal oral liquid

目的确定冬虫夏草多糖脂质体口服液质量标准。方法用蒽酮 硫酸比色法测定冬虫夏草多糖浓度;用透析法测定其包封率。结果平均加样回收率为98 73% ,RSD为1 4 8% ;冬虫夏草多糖浓度为6 4 4 8×10 -2 mol·L-1,包封率为31 77%。

Objective To establish the quality standards for the Cordyceps sinensis Sacc polysaccharide liposomal oral liquid.Methods The content of Cordyceps sinensis Sacc polysaccharide in Cordyceps sinensis Sacc polysaccharide liposomal oral liquid was determined by anthrone-sulfuric colorimetry.The entrapment effciency of Cordyceps sinensis Sacc polysaccharide liposomal oral liquid was determined by dialysis method.Results The average recovery was 98.73% and RSD was 1.48% (n=5).The content of Cordyceps sinensis Sacc polysaccharide was 6.448×10~ -2 mol·L~ -1 .The entrapment effciency of the Cordyceps sinensis Sacc polysaccharide liposomal oral liquid was 31.77%.Conclusions These methods can be used for the quality standards for the Cordyceps sinensis Sacc polysaccharide liposomal oral liquid.