2种仙人掌多糖对S180小鼠红细胞免疫功能影响的研究

Study on the effects of two kinds of cactus polysaccharide on erythrocyte immune function of S180 mice

目的:研究仙人掌多糖对S180小鼠红细胞免疫功能的影响。方法:应用药理方法及化学试剂盒进行测定。结果:仙人掌多糖可增加荷瘤小鼠肿瘤红细胞花环率,提高红细胞C3b受体花环促进率,降低红细胞C3b受体花环抑制率,提高红细胞表面唾液酸含量。药用仙人掌多糖中剂量组及食用仙人掌多糖高剂量组效果显著(P<0.01)。结论:仙人掌多糖可以改善荷瘤小鼠红细胞免疫功能,可能是其抗肿瘤作用的机制之一。

Objective: To study the effects of two kinds of cactus polysaccharide on erythrocyte immune function in S180 mice. Method: Classical pharmaceutical method and test kit. Result: The cactus polysaccharide increased the content of RBC-CaR, RFER, decreased the content of RFIR, raised the content of sialic acid. And the effect of median dose group of medical cactus polysaccharide and high dose group of edible cactus polysaccharide is very remarkable(P<0.01)compared with model group. Conclusion: The cactus polysaccharide improved the erythrocyte function of tumor-mice, which may be one of anti-tumor mechanisms.