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Synthesis, Structure and Biological Activities of 2-(4-Methoxybenzoyl)-N-phenyl- 2-(1,2,4-triazol-1-yl)thioacetamide

Synthesis, Structure and Biological Activities of 2-(4-Methoxybenzoyl)-N-phenyl- 2-(1,2,4-triazol-1-yl)thioacetamide
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摘要 The title compound, 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, ~ 1H NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity. The title compound, 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, ~ 1H NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity.
出处 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2005年第3期280-283,共4页 高等学校化学研究(英文版)
关键词 1 2 4-Trizole THIOAMIDE Crystal structure Biological activities 1,2,4-Trizole, Thioamide, Crystal structure, Biological activities
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