1000例胸液腺苷脱氨酶检测结果随访分析

Measurements of pleural adenosine deaminase in 1000 cases and follow-up results

目的 探讨检测胸液中腺苷脱氨酶(ADA)对结核性胸膜炎与恶性胸腔积液的鉴别价值。方法 胸液ADA测定按Giusti方法进行,并对患者的病程和结局进行随访。结果 检测1 0 0 0例患者,ADA >35U L为升高,共395例,ADA≤35U L为正常,共6 0 5例。结核性胸液392例,其中ADA升高36 7例,ADA正常2 5例(6 .3%)。恶性胸腔积液2 6 0例,其中ADA正常2 4 6例,升高1 4例(5 .3%)。结论 胸液ADA检测可作为结核性胸腔积液与恶性胸腔积液鉴别诊断的辅助指标。

ObjectiveTo explore the value of the adenosine deaminase (ADA) inspection in the pleural effusions to differentiating tuberculous pleuritis from malignant pleural effusions. Methods The process of measure of the ADA inspection in pleural effusions was going along as the method of Giusti which should be known the development and result of the disease of the patients in the later 8 years. Results Among the 1 000 routines of the patients inspected,there were 395 routines, ADA>35 U/L, which was considered to be high. And 605 routines, ADA≤35 U/L, which was considered to be normal.There were 392 whose ADA were high in 367 routines who were diagnosed tuberculous pleural effusions,and 25(6.3%) routines whose ADA were not high.260 routines who were diagnosed malignant pleural effusions, there were 246 routines normal, but 14(5.3%) routines were high. Conclusions The result of the inspection of the ADA can be used as a standard of differentiating the tuberculous pleural effusions from malignant pleural effusions.