复方大黄粉治疗溃疡性结肠炎临床疗效观察

Clinical observation on effect of the rhubarb powder compound in the treatment of ulcerate colonitis

目的:探讨复方大黄粉治疗溃疡性结肠炎临床疗效。方法:118例溃疡性结肠炎患者随机分为2组,治疗组59例,采用复方大黄粉悬液保留灌肠,每日1次,10天为1个疗程。对照组59例,采用柳氮磺吡啶液保留灌肠,每日1次,10天为1个疗程。6个疗程后观察腹痛、腹泻等症状改变,并复查肠镜。结果:治疗组59例,治愈率81.4%(48/59),总有效率91.5%。对照组59例,治愈率40.0%(23/59),总有效率71.2%。经χ2检验,两组治愈率及总有效率二者均有显著性差异(P<0.01)。结论:复方大黄粉灌肠治疗溃疡性结肠炎临床疗效较好,优于柳氮磺吡啶液组。

Objective:To observe the effect of the rhubarb powder compound in the treatment of ulcerate colonitis.Methods:118 patients with ulcerate colonitis were randomly divided into 2 groups.The 59 patients in the treated group were treated with the rhubarb powder compound enema holding,once a day,each therapeutic course was 10 days.The 59 patients in the control group were treated with SASP enema holding,once a day,each therapeutic course was 10 days.The therapeutic effect was evaluated after 6 courses.Colon scope was carried out and symptoms such as bellyache and diarrhea was observed before and treatment.Results: Cure rates were 81.4%(48/59)in treatment group and 40.0%(23/59)in the controls(P<0.01).Effective rates were 91.5%(54/59)in treatment group and 71.2%(42/59)in the controls(P<0.01).Conclusions:The clinical therapeutic effects of the rhubarb powder compound enema holding in the treatment of ulcerate colonitis are much better than those of SASP group.