促进肌腱愈合及预防肌腱粘连的研究进展

THE RESEARCH PROGRESS OF ACCELERATING TENDON HEALING AND PREVENTING TENDON ADHESION

目的 较全面了解在促进肌腱愈合和防止肌腱粘连的材料和方法的现状,为今后相关研究及临床应用提供必要参考。 方法 广泛查阅近年国内外相关文献,总结分析肌腱愈合的方式,及促进肌腱愈合的药物和方法。 结果 肌腱愈合由内、外源愈合共同作用,以内源性愈合方式为主,同时又与腱鞘、腱纽及滑液等条件有密切联系;肌腱粘连多是由于外源性愈合参与过多及腱周损坏所致。通过修复或重建腱周组织、电刺激、理疗、加入药物、生长因子及基因干预等,可促进肌腱愈合;而通过修复腱鞘或采用代用品、加入药物及改进缝合技术等能有效预防肌腱粘连。 结论 通过恰当的中西医治疗方法和技术,可在促进肌腱愈合速度、提高愈合质量的同时。

Objective To study the status quo of the methods and materials for accelerating the tendon healing and preventing the tendon adhesion as to provide an essential reference for future research and clinical application. Methods The recent articles on methods of accelerating tendon healing and preventing tendon adhesion were extensively reviewed. Results Tendon healing was decided by the co effects of both endogenous and exogenous ways, and the former was more important. It was affected by the tendon sheath, vincula tendinum and synovial fluid as well. Tendon adhesion was mostly caused by excessive participation of exogenous healing factors and serious damage of the situations around the tendon. Tendon healing was accelerated by methods like repairing, reconstruction of peri tendon tissues, electric stimulation, physiotherapy, adding herbs or growth factors, and gene intervention. Tendon adhesion was reduced or prevented by methods like the restoration of tendon sheath, using substitutions, adding herbs drugs, and improving suturing techniques. Conclusion Via the appropriate methods and techniques combining the Chinese traditional and modern medicine, tendon healing can be accelerated and the quality of tendon healing can be improved.