颈髓损伤晚期损伤程度及损伤后瘫痪时间对肺功能的影响

Effect of the degree and the duration of chronic cervical cord injury on pulmonary function

目的:探讨颈髓损伤晚期患者损伤程度及损伤后瘫痪时间对肺功能的影响.方法:对40例颈髓损伤晚期患者进行ASIA运动评分,并测定最大肺活量(VCMAX)、时间肺活量(FVC)、第一秒最大呼气量(FEV1)、呼气高峰流量(PEF)及损伤后瘫痪时间,观察各项肺功能指标变化.结果:40例颈髓损伤晚期患者肺功能皆下降,ASIA运动评分与VCMAX、FVC、FEV1、PEF成正相关;完全性损伤组与不完全性损伤组间VCMAX、FVC、FEV1、PEF有显著性差异(P＜0.05);本组完全性损伤组或不完全性损伤组中,C3～5与C6～8节段损伤患者的VCMAX、FVC、FEV1、PEF均无显著性差异;损伤后瘫痪时间与VCMAX无相关性,而与FVC、FEV1、PEF呈正相关.结论:颈髓损伤晚期患者肺功能均下降,肺功能改变与脊髓损伤程度及损伤后瘫痪时间有关.

Objective:To investigate the effect of the degree and the duration of chronic cervical cord injury on pulmonary function.Method:To test the VCMAX?FVC?FEV1?PEF and ASIA score in 40 patients with chronic cervical cord injury.Result:The level of pulmonary function showed lower than normal in 40 patients with chronic cervical cord injury,ASIA score was positively correlated with VCMAX?FVC?FEV1 and PEF;There were significant differences of VCMAX?FVC?FEV1 and PEF between complete lesions group and incomplete lesions group.In complete or incomplete lesions group,there were no significant differences among VCMAX?FVC?FEV1 and PEF in different levels.The duration of chronic cervical cord injury was no correlated with VCMAX,but it was positively correlated with FVC?FEV1 and PEF.Conclusion:Pulmonary function in chronic spinal cord injured patients is lower than normal,the change accord with the degree and the duration.