摘要
目的:探讨检测新蝶呤(Npt)及C-反应蛋白(CRP)对冠心病(CAD)患者的临床价值。方法:观察30例稳定性心绞痛(SAP)、32例不稳定性心绞痛(UAP)、28例急性心肌梗死(AMI)和40例健康体检者(对照组)血清中Npt及CRP的水平,按冠状动脉(冠脉)造影狭窄病变支数分为3组,进行相应比较,并观察冠脉病变支数及其狭窄程度与Npt和CRP的相关性。结果:CAD组血清Npt、CRP水平高于对照组,差异均有统计学意义(均P<0.05),AMI及UAP组Npt、CRP水平明显高于SAP组(均P<0.05),CAD组血清Npt、CRP水平与冠脉狭窄病变支数及狭窄程度无直线相关性(均P>0.05)。结论:血清Npt、CRP的升高可作为CAD患者发生急性冠脉事件的预测指标。
Objective: To study the clinical value of Neopterin (Npt) and C-Reactive Protein(CRP) in patients with coronary artery disease (CAD). Methods: To observe and compare serum levels of Npt and CRP in 30 cases with stable angina pectoris (SAP), 32 cases with unstable angina pectoris (UAP), 28 cases with acute myocardial infarction (AMI) and 40 healthy controls. Results: Serum levels of Npt and CRP in CAD group were significantly higher than those in control group (P < 0.05), Npt and CRP in AMI and UAP were significantly higher than those in SAP group (P < 0.05). There is no relationship between branches of coronary artery lesions and narrow degree of coronary artery and serum levels of Npt and CRP (P > 0.05). Conclusion: This study suggests that the increase of Npt and CRP can be as predictable marker for patients with acute coronary syndromes.
出处
《天津医药》
CAS
北大核心
2005年第5期257-259,共3页
Tianjin Medical Journal
