中晚期原发性肝脏恶性肿瘤291例临床研究

Clinical study of 291 cases with advanced primary malignant hepatic tumor.

本文收集原发性中晚期肝脏恶性肿瘤291例,均经手术、病检所证实。其中Ⅰ期肝切除133例,Ⅰ期肝切除率45.7%,手术死亡率3.76%。1、3、5年生存率分别为77.8%、38.9%、16.7%,8例已生存7年以上,其中3例已生存10年以上,至今尚存活。109例不能切除肝癌的综合性治疗,其中82例行血管栓塞治疗,全部病例肿瘤均有不同程度缩小,12/20例缩小1/3以上,以瓷粉栓塞效果最佳。一年以上的生存率52.63%,Ⅱ期切除率达36.84%(平均18.29%)。

The paper collected 291 cases with advanced primary hepatic malignant tumors which were comfirmed by laparotomy and pathology. Hepatectomy were operated on 133 casese at the first laparotomy and primary resectability rate was 45.7%. The operative mortality was 37.7%. The survival rate at 1, 3, 5 years was 77.8%, 38.9% and 16.7%, respectively. Eight cases survived more than 7 years. Three cases of 8 survived more than 10 years and was still alive. One hundred nine cases received comprehensive therapy. The embolic chemotherapy with different emholizing agents was used in 82 cases and the results showed embolizing effect of porcelain powder better than the other agents. After comprehensive therapy, the tumors became smaller than before in different extent. The survival rate more than one year was 52.63%. The second resectability rate reached 36.84% (average 18.29%).