口腔颌面部静脉畸形及血管瘤的激光治疗研究

Clinical study on laser therapy of the venous malformations and hemangioma in oral and maxillofacial regions

目的探索激光治疗口腔颌面部静脉畸形与血管瘤的最佳方案。方法自1999年6月至2002年7月,上海第二医科大学附属第九人民医院口腔医学院共收治各种静脉畸形与血管瘤病例2481例。分别应用连续式CO2、Nd:YAG和Krypton激光及脉冲染料激光、超脉冲CO2激光治疗。激光照射方式有单纯照射、手术翻瓣照射、光动力疗法。结果经2～5年随访观察发现,1966例获得显著疗效,显效率为79.24%,355例有效,有效率为14.31%,160例疗效较差(6.45%)。结论激光是治疗口腔颌面部各种静脉畸形与血管瘤的有效方法,治疗的关键是正确掌握适应证。

Objective To try to find the best method of laser therapy for the management of venous malformation and hemangioma in oral and maxillofacial regions. Methods From June, 1999 to July, 2002, 2 481 cases of venous malformations and hemangiomas were treated by several kinds lasers in our department. The lesions included port-wine stains, venous malformations, telangiectasia and hemangioma . The lasers used were continuous wave CO_2, Nd:YAG and Krypton lasers, pulsed dye laser and ultra-pulsed CO_2 lasers. The treatment modalities were direct irradiation, irradiation after surgical flap raising and photodynamic therapy. Results Follow up between 2-5 years revealed the treatment results as follows: excellent is 79.24%, good is 14.31% and poor is 6.45%. Conclusions Laser therapy is one of the best method to treat venous malformations and hemangiomas. The key point is to apply different lasers properly.