低强度超声促进兔骨-肌腱结合部早期恢复的初步观察

Primary observation of low-intensity ultrasound on early healing of bone-tendon junction

目的: 观察低强度超声对骨-肌腱结合部位恢复的影响。方法: 建立兔髌骨部分切除模型, 16只成年雌性新西兰白兔随机分为2组, 超声组每日接受低强度超声刺激, 对照组给予假刺激。术后6、12周处死动物取标本(n=4) 做大体和病理组织学观察。结果: 大体见超声组腱-骨结合部愈合较早; 组织学观察显示超声组6周可以看到骨-肌腱结合部纤维母细胞、成骨细胞增生活跃, 12周出现软骨带, 部分胶原纤维长入新生的骨质中, 恢复较对照组迅速。结论: 低强度超声可以促进骨肌腱结合部位的早期恢复。

Objective:To explore the effects of low-intensity ultrasound on healing of bone-tendon junction in a patellar tendon complex. Method: Animal model of partial patellectomy in 16 mature female New Zealand White rabbits (18-week-old) were established and randomly classified into 2 groups. The ultrasound group was given low-intensity ultrasound exposure daily while the control group had sham exposure. patellar tendon complex was harvest at 6、12 weeks after operation for gross and histological examinations. Result: The histological examination revealed that at 6 weeks, the ultrasound group, junction between bone and tendon was filled with proliferated fibroblasts, the cartilage zone occurred at 12 weeks,fibers extended continuously from tendon into bone. The gross and histological observations showed that the tissue healing of ultrasound group was quicker than those of the control group. Conclusion: low-intensity ultrasound can accelerate early healing of bone-tendon junction.