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TGF-β信号转导与肿瘤

TGF-β Signaling Transduetion and Carcinoma
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作者 王守立 杨光华 步宏
机构地区 四川大学华西医院病理科
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2004年第8期476-477,共2页 Chinese Journal of Clinical Oncology
关键词 转化生长因子Β 信号 转导 肿瘤
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献17

  • 1[1]Djaborkhel R, Tvrdik D, Eckschlager T, et al. Cyclin A downregulation in TGFbeta1-arrested follicular lymphoma cells [J].Exp Cell Res, 2000, 261(1):250～259
  • 2[2]Liu X, Sun Y, Ehrlich M, et al. Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kipl mislocalization [J]. Oncogene, 2000, 19(51):5926～5935
  • 3[3]Shariat SF, Kim JH, Andrews B, et al. Preoperative plasma levels of transforming growth factor beta(1) strongly predict clinical outcome in patients with bladder carcinoma[J]. Cancer, 2001, 92(12):2985～2992
  • 4[4]Ramont L, Pasco S, Homebeck W, et al. Transforming growth factor-betal inhibits tumor growth in a mouse melanoma model by down-regulating the plasminogen activation system [J]. Exp Cell Rcs, 2003, 291(1):1～10
  • 5[5]de Caestecker MP, Piek E, Roberts B, et al. Role of transforming growth factor-β signaling in cancer [J]. J Natl Cancer Inst, 2000,92(17):1388～1402
  • 6[6]Turco A, Scarpa S, Coppa A, et al. Increased TGF-beta type 1Ⅱreceptor expression suppresses the malignant phenotype and induces difffrentiation of human neuroblastoma cells [J]. Exp Cell Res, 2000, 25(1):77～85
  • 7[7]Inman GJ, Allday MJ. Resistance to TGF-betal correlates with a reduction of TGF-beta type Ⅱ receptor expression in Burkitt′s lymphoma and Epstein-Barr virus-transformed B lymphoblastoid cell lines[J].J Gen Virol, 2000, 81(Pt 6):1567～1578
  • 8[8]Yanagisawa K, Uchida K, Nagatake M, et al. Heterogeneities in the biological and biochemical fi nctions of Smad2 and Smad4mutants naturally occurring in human lung cancers [J].Oncogene, 2000, 19(19):2305～2311
  • 9[9]Xu J, Attisano L. Mutations in the tumor suppressors Smad2 and Smad4 inactive transforming growth factor beta signaling by targeting smads to the ubiqutin-proteasome pathway [J]. Proc Natl Acad Sci USA, 2000, 97(9):4820～4825
  • 10[10]Tanaka S, Mori M, Mafune K, et al. A dominant negative mutation of transforming factor-beta receptor type ц gene in microsatellite stable oesophageal carcinoma[J]. BrJ Cancer, 2000, 82:(9) 1557～1560

二级参考文献14

  • 1[1]Wong SF, Lai LC. The role of TGFbeta in human cancers. Pathology, 2001;33:85～92
  • 2[2]Bouche M, Canipari R, Melchinna R et al. TGF-β autocrine loop regulates cell growth and myogenic differentiation in human rhabdomyosarcoma cell. Faseb J, 2000;14:1147～58
  • 3[3]Romeo DS, Mizdl SB. Partial purification of an immunosuppressive protein from a human tumor cell line and analysis of its relationship to transforming growth factor beta. Cell Immunol, 1989;122:483～92
  • 4[4]Molennar WM, Oosterhuis JW, Kamps WA. Cytologic"differentiation" in childhood rhabdomyosarcomas following polychemotherapy. Hum Pathol, 1984;15:973～9
  • 5[5]Massague J, Blain SW, Lo RS. TGFβ signaling in growth control, cancer, and heritable disorders. Cell, 2000;103:295～309
  • 6[6]Wrana JL, Attisano L, Wieser R et al. Mechanism of activation of the TGFβ receptor. Nature, 1994;370:341～7
  • 7[7]Markowitz S, Wang J, Myeroff L et al. Inactivation of the type Ⅱ TGF-beta receptor in colon cancer cells with micro-satellite instability. Science, 1995;268:1336～8
  • 8[8]McCune BK, Patterson K, Chandra RS et al. Expression of transforming growth factor-beta isoform in small round cell tumors of childhood. Am J Pathol, 1993;142:49～58
  • 9[9]Ignotz RA, Massague J. Type β transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts. Proc Natl Acad Sci USA, 1985;82:530～4
  • 10[10]Olson EN, Sternberg E, Hu JS et al. Regulation of myogenic differentiation by type beta transforming growth factor. J Cell Biol, 1986;103:1799～805

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中国肿瘤临床
2004年 第8期

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