兔脑炎原虫病脑组织的病理形态学观察

Observations of the Brain Lesions in Rabbits with En-cephalitozoonosis

兔患脑炎原虫病时脑组织的病损主要是特异性肉芽肿和非化脓性脑炎。肉芽肿有３种类型：即上皮细胞性、增生性和坏死性肉芽肿。非化脓性脑炎有局灶性和弥漫性之分。隐性感染病兔的肉芽肿主要位于脑白质，肉芽肿周围有局灶性非化性脑炎变化。有症状病兔的肉芽肿不仅存在于白质，而且累及灰质；非化脓性脑炎弥漫性发生。在脑血管的内皮细胞中发现假囊，小血管中有血栓形成；受累的神经细胞中发现有较多量的脑炎原虫。

The brain lesions of rabbits with encephalitozoosis are mainly specificgranulomatosis and non-suppurative encephalitis, The former has 3 types,i.e. epithe-lial, productive and necrotic granulomas, Non-suppurative encephalitis is divided intolocal and diffusive ones。 In the latent infectious rabbits , the granuloma is chiefly locatedin the white matter。 There are the local non-suppurative encephalitis lesions around thegranulomas。 However , the granulomas of clinically apparent infectious rabbits are notonly appeared in the white matter, but also found in grey matter, Non-suppurative en-cephalitis is observed in all of central nervous system。 The pseudocysts are seen in thevessel epithelia, Occasionally thrombi are observed in small vessels。 There are a lot oforganisms in nervous cells。