抗磷脂抗体致病机理的研究进展

New development of antiphospholipid antibodies leading to pregnancy loss

本文对抗磷脂抗体导致妊娠丢失的相关机理的研究进展加以综述,并结合近年来对抗心磷脂抗体的研究,阐述了抗磷脂抗体的免疫特性及其导致妊娠丢失等疾病的致病机理。

Antihospholipid antibodies are autoimmune globins,mainly including anticardiolipin antibodies and lupus anticagulant.Recently studies have reported the presence of antibodies in patients with pregnancy loss.These antibodies are felt to be etiologically important in pregnancy loss.We will study antiphospholipid antibodies and its associasion with pregnancy loss in immune characterization and pathogenic mechanism.