丹参对休克猫血液β－内啡呔及精氨酸加压素的影响

Saivla miltiorrhizae on plasma β-endorphin andarginine vasapressin in cats with hemorrhagicshock

观察失血性休克猫血液β－内啡呔（β－ＥＰ）及精氨酸加压素（ＡＶＰ）的变化，并探讨丹参的治疗作用。结果：猫休克５ｍｉｎ后，血浆β－ＥＰ及ＡＶＰ即达峰值，以后逐步降低，至休克后１５５ｍｉｎ恢复至休克前水平。两者变化趋势基本一致，呈显著相关。经丹参治疗后，血浆β－ＥＰ及ＡＶＰ较治疗前及休克后相应时程均显著降低。其机理不明，有待进一步研究。

we observed the alterations in the concentration of plasma β-endorphin (β-EP) and arginine vasopressin(AVP)on which we studied the effect of salvia miltiorrhizae in cats with hemorrhagic shock.Itwas found that plasma β-EP and AVP increased tothe peak value five minutes after shock began,andthen, they declined slowly and fell to the pre-shocklevel 155 minutes after shock,The trends of changesin β-EP and AVP were essentially the same and cor-related significantly。 After the cats were treated withsalvia miltiorrhizae,the elevated β-EP and AVP de-creased remarkably.This result suggests that salviamiltiorrhizae can affect the metabolism ofβ-EP andAVP,The mechanism of these changes are not clearand remains to be further studied。