摘要
对80例小儿肾脏疾病患者的尿Tamm+Horsfall蛋白(THP)24h含量进行检测,并与正常组比较。结果:肾功能不全组THP低于正常,单纯肾病极期高于正常,急性肾炎早期与正常无差异。肾功能不全时,随血BUN升高,尿THP相应下降,呈负相关;肾小球疾病极期伴有一过性氮质血症与肾功能不全时出现氮质血症患儿的尿THP含量有明显差异,临床上具有鉴别诊断意义。
24-hour urine Tamm-Horsfall protein
(THP)determined in 80 children wi,hrenal disease wascompared with that in normal controls.The
authorsbund that the TH P in renal insufficiency patientswas below normal level,that in patients
at the climaxof simple nephrosis was higher than normal ,and thatin patients in the early stage
of acute nephritis wassimilar to normal.In renal dysfunction,BU N was in-creased , and urine TH
P was correspondingly de-creased , which showed a negative correlation be-tween the two
opposite changes,Significant differ-ence in the urine THP was found between translentazotemia
at the climax of glomerular diseads andazotemia due to renal dysfunetion,which appearedto be
of diagnostic significance.
出处
《中国危重病急救医学》
CAS
CSCD
1994年第4期209-211,共3页
Chinese Critical Care Medicine
关键词
肾功能衰竭
儿童
蛋白
THP
Tamm-Horsfall protein
renalinsufficiency
peri-renal
azotemia