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转染TRAIL的神经干细胞对神经胶质瘤凋亡的诱导作用 被引量：1

Glioma cell apoptosis induced by TRAIL neural stem cells
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摘要 神经干细胞对颅内胶质瘤有很强的趋向作用,而对正常脑组织无此特性。TRAIL能选择性地促使肿瘤细胞凋亡而对正常组织无毒性。本文就神经干细胞、TRAIL及神经干细胞转染TRAIL后与胶质瘤的关系作一综述。 Neural stem cells (NSCs) display strong tropism for intracranial glioma, but not for normal brain tissue; tumor necrosis factor-related apoptosi s-inducing ligand (TRAIL) preferentially trigger the apoptosis in tumor cells ve rsus normal cells. This article will review the relationship among NSCs, TRAIL a nd glioma cells.
作者 胡钧涛 涂汉军
机构地区 郧阳医学院附属太和医院神经外科
出处 《中华神经医学杂志》 CAS CSCD 2005年第5期531-533,共3页 Chinese Journal of Neuromedicine
关键词 干细胞 神经胶质瘤 肿瘤坏死因子相关的凋亡诱导配体 凋亡 Stem cells Glioma TRAIL Apoptosis
分类号 R739.4 [医药卫生—肿瘤]
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参考文献16

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二级参考文献13

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共引文献25

同被引文献12

引证文献1

二级引证文献8

中华神经医学杂志
2005年 第5期

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