中药治疗200例HIV感染者/AIDS患者的结果分析

Utilization of traditional Chinese medicines in the treatment of 200 people living with HIV/AIDS.

目的 分析中药治疗艾滋病病毒(HIV)感染者/艾滋病(AIDS)患者后的实验室数据及临床变化特点。方法 采用治疗前后自身对照的方法,对1 999～2 0 0 2年在北京佑安医院接受中药治疗的2 0 0例HIV感染者/AIDS患者的实验室数据及临床症状进行分析。结果 (1 )病毒载量(VL)的变化:接受治疗的2 0 0例中,VL下降超过1log 2例(%) ,VL下降超过0 .5log 1 8例(9%)。(2 )CD+ 4 细胞数的变化:在CD+ 4 ≥2 0 0 /μl的1 2 9例患者中,治疗后5 6例(43. 4%)患者的CD+ 4 细胞数上升>5 0 /μl;在CD+ 4 细胞数<2 0 0 /μl的71例患者中,只有6例(8 5 %)CD+ 4 细胞数上升>5 0 /μl。同时,有85 %的患者在接受中药治疗后临床症状都有不同程度的改善。结论 中药能部分改善HIV感染者/AIDS患者的免疫功能和临床症状,但在病毒抑制方面的作用较弱。中药治疗时间越早,疗效越好;晚期治疗则疗效较差。

Objective To evaluate the variation of laboratory data and clinical symptoms for people living with HIV/AIDS in the treated with traditional Chinese medicines(TCM).Results (1) Variation of viral load:reduction of viral load more than 1log in 2 cases(1%) and 0.5log in 18cases(9%) after the treatment with traditional medicines. (2) Variation of CD+_4 count:among 129 cases with CD+_4 count over 200/μl,56 cases(43.4%) increased their CD+_4 count by more than 50/μl after the treatment.However,only six subjects (8.4%) in the group of CD+_4 less than 200/μl increased CD+_4 by more than 50/μl. In the meantime,more than 85% of people with HIV/AIDS improved their clinical syndrome after the treatment with traditional Chinese medicines.Conclusion (1) TCM can strengthen the immune system partly and improve the life quality of people with HIV/AIDS.However,traditional Chinese medicines prove to be relatively weak in inhibiting HIV.(2)The earlier people with HIV/AIDS use traditional Chinese medicines, the better effectiveness reveals.However,the effect will be poor if TCM are used in a later stage of the disease.