不对称合成4-氧代-2,4-二苯基-丁酸酯
Asymmetric synthesis of 4-oxo-2,4-diphenylbutanoate ester
摘要
手性醇衍生的α-重氮苯乙酸酯与N-(苯乙烯基)-吗啉在铜盐催化下的反应,能够以高度的化学产率制备手性的4-氧代-2,4-二苯基-丁酸酯,产物中两种非对映异构体的比例达到2:1.
The reaction of phenyldiazoacetates derived from chiral alcohols with N-(1-styryl)morpholine catalyzed by copper salts provided chiral 4-oxo-2,4-diphenyl-butanoate esters in good yield. The diastereomer ratio of the product was up to 2:1.
出处
《苏州大学学报（自然科学版）》
CAS
2005年第2期73-76,共4页
Journal of Soochow University(Natural Science Edition)
基金
江苏省重点实验室开放基金(S8109104)
参考文献12
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