摘要
本文观察了老年前期和老年期不同类型高血压患者１０９例的超氧化物歧化酶（ＳＯＤ）及其同工酶的变化，并与非高血压患者５１例对照，结果发现，总ＳＯＤ及其同工酶随年龄增长而呈下降趋势；总ＳＯＤ活力及铜锌超氧化物歧化酶和锰超氧化物歧化酶活力随高血压病的病情加重而明显降低，与非高血压患者比较均有显著性差异（Ｐ＜０．０１）。
The activities of total serum superoxide dismutase(SOD);Cu ,Zn-SOD and Mn-SOD in 109 patients with primary hypertension,including 55 aged 45-59 (presenile,stageⅠhypertension 20,Ⅱ18, Ⅲ 17) and 54 aged 60-82(senile,Ⅰ20,Ⅱ 23, Ⅲ 11) were determined together with a control group of 51 patients without hypertension including 24 aged 44-59(presenile)and 27 aged 60-73(senile).The results showed that total SOD activity decreased with increase of age.And the activities of total SOD;Cu,Zn-SOD and Mn-SOD significantly decreased with increasing severity of hypertension.Furthermore significant difference between hypertensives and non-hypertensives was found.
出处
《中国循环杂志》
CSCD
1994年第4期203-205,共3页
Chinese Circulation Journal
关键词
原发性
高血压
衰老
超氧物歧化酶
Primary hypertension
Senility
Superoxide dismutase
