济阳县15～40岁人群乙型肝炎病毒感染标志调查

Investigation on HBV Infection Markers in Jiyang,shandong

目的 了解乙型肝炎(乙肝)病毒(HBV)感染标志的分布情况。方法 2 0 0 3年11月在山东省济阳县开展了15～4 0岁人群HBV感染标志分布的横断面调查,共采集合格静脉血1994人份。乙肝病毒表面抗原(HBsAg)、乙肝病毒表面抗体(抗HBs)、乙肝病毒核心抗体(抗HBc)均用固相放射免疫(SPRIA)法检测。结果 15～4 0岁人群HBsAg、抗HBs、抗 HBc和HBV感染率分别为6 5. 2 %、2 4 .77%、30 . 99%和4 3 .6 3%。HBsAg流行率随年龄的增长而升高,男女性别之间HBsAg流行率的差异无显著的统计学意义。结论 该次调查正值我国将乙肝疫苗纳入儿童计划免疫之际,此调查可为之提供本底资料。

Objective To evaluate the distribution of HBV infection marker. Methods A cross-sectional study was carried out in 15-40 years old people in Jiyang, Shandong. The HBsAg, anti-HBs and anti-HBc serological markers were screened by RIA kit. Results The results showed that the HBsAg positivity,anti-HBs positivity and HBV prevalence rate were 6.52%,24.77%, and 43.63%. Conclusion The HBsAg positivity rate increased along with the age increasing(P<0.05),but there is no statistical significance between man and woman.