学龄前儿童蛲虫病的流行现状与防治

OBSERVATION PREVALENCE AND TREATMENT OF ENTEROBIASIS IN CHILDREN

采用透明胶纸拭肛法对徐州城乡38所幼儿园共9297名儿童进行蛲虫流行情况调查，结果发现蛲虫卵阳性者3223名（34．7％）。对其中12所共2660名儿童中阴性者再连续检查两天次，累计阳性率达55．4％。城、乡以及男、女性别儿童感染率均无显著性差异（P＞0．05）。3～6岁间，年龄与感染率呈显著正相关（r＝0．998，P＜0．025）。感染者的手指、内裤、床单和坐椅上均查到感染性卵。52．7％感染者具有肛痒症状。表明蛲虫病在我区城乡儿童中流行广泛、危害严重，急待防治。对2358名感染者分别采用不同剂量丙硫咪唑与复方甲苯达唑治疗，虫卵阴转率达97．7％～98．9％，效果显著，副反应轻微。表明这两种药小剂量顿服，适用于现场普治，值得推广应用。

Thc enterobiasis prevalence in 38 kindergatens of xuzhou city and rural areses was examined during 1991-1992. Of 9297 children, 3223 (34.75% )were found positive with pinworm eggs. Of 9297 children, 266O were examincd three times sequently. The accumulative infection rate was 55.4%.No significant difference in prcvalence was found between city and ruralareas. Eggs of pinworm were aIso detected on fingers, pants, bed linens and chairs; 52.7% of infected children suffered from perianal itching. Albendazole was used to treat 1230 patients with enterobius infection. It was given orally with a dose of 100mg or 200mg once a day. Concurrently mebendazole composite was used to treat 1128 patients 1 or 2 tablets orally once a day. The results showed that the egg negative conversion rates of 2 weeks after treatment were 97.7% and 98.3% for albendazole and 97.8% and 98.9% for mebendazoIe composite respectively, and that side reactions were mild and transient. The theropoutic trial showed that albendazole or mebendazole composite with a little of the dose is a convenient drug on the sopt treatment to control enterobiasis.