苯妥英外用对兔创面愈合的实验研究

EXPERIMENTAL STUDY OF THE EFFECTOF PHENYTOIN ON THE HEALING OF WOUND OF RABBIT/

将苯妥英外用于兔创面上进行自身对照实验，采用创面缩小面积、创面愈合天数、创面组织的光镜及电镜检查，以及创面细菌定量检测等观测指标，发现苯妥英外用有加速创面的愈合，缩短愈合天数；促进创面健康肉芽组织的生长及加速创缘上皮组织向创面中心的生长；减少创面细菌数等作用。

An experiment on the effect of phenytoin onthe healing of wounds of rabbits with the selfcontrol was otiserved from the followingparameters: the reduction of surface area ofwound, the time required for the healing ofwound, examination of the wound tissues bylight and electronic microscope , and the bacterialcounts of the wound. It was noted thatphenytoin was capable to increase the rate ofwound healing, reduce the time of woundhealing, enhance the growth of healthygranulation tissue, enhance the growth ofepithelium fron the periphery to the centcr ofthe wound and reduce the bacterial counts on thewound.