摘要
依据近年来国内外相关文献,对非典型抗精神病药物的作用机制、临床应用及药物不良反应进行综述。非典型抗精神病药物除了治疗精神分裂症外,还用于治疗心境障碍、边缘性人格障碍、强迫症、抽动-秽语综合征等精神障碍。研究较多的不良反应包括体重增加及血脂、血糖、催乳素水平升高等。
Atypical antipsychotics clinically manages schizophrenia as well as several affective disorders, such as mood disorder, border personality disorder, obsessive-compulsive neurosis and Tourette's syndrome. The common adverse reactions that the atypical antipsychotics cause include weight gain, hyperglycemia, hyperlipidemia and increment of prolactin secretion. This review summarized the mechanism, pharmacotherapeutics and safety of atypical antipsychotics.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2005年第5期540-544,共5页
Chinese Journal of New Drugs