血液流变性改变对动脉化静脉皮瓣成活的影响

ABSTRACTSEXPERIMENTAL STUDY ON THE RELATIONSHIP BETWEEN THE SURIVAL OFARTERIALIZED VEIN FLAPS AND THE CHANGES OF HEMORHEOLOGY

在大白鼠胸腹部形成动脉化静脉皮瓣和动、静脉皮瓣，术后不同时间进行血液流变学检测，同时观察皮瓣的成活情况。结果显示，动脉化静脉皮瓣术后血小板聚集率，血液粘度及纤维蛋白原含量明显升高，皮瓣成活情况不如动、静脉皮瓣。提示术后血液流变性改变可能是影响动脉化静脉皮瓣成活的重要因素之一。

he experiment was earied out on the a boomen of the whiterats. The epigastric vein wasarterialized by means of anastomcois with the femoral artery, lateral thoracic vein was reserved as aefferent vessel. The changes of hemorheology were mesured after arterialization, and were comparedwith the changes in the normal A-V skin flaps. The levels of platelet, aggreation, blood viscosityand plasma fibrinogen in arterialized vein flape were signmeantly higher than that in A-V flaps. ASa result of thiS exporiment, rate survival the of the arterialized vein flaps was not as good as that of theA-V flaps. The results suggested that the changes of hemeorheology would influence the bloodcirculation and the survival of the arterialized vein flaps.