Preparation and Analysis of Acylated Insulin with Dehydrocholic Acid

Preparation and Analysis of Acylated Insulin with Dehydrocholic Acid

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摘要 Insulin was chemically modified with dehydrocholic acid without the use of protecting agents and the main monoacylated insulin. ε-NB29-Dehydrocholyl insulin was obtained selectively and analyzed by PAGE, HPLC and MALDI-TOF-MS.

作者 TaoHUANG KaiXunHUANG

机构地区 DepartmentofChemistry

出处《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第6期743-746,共4页 中国化学快报（英文版）

基金 supported by the National Natural Science Foundation of China(Project No.20371018) the Research Fund from the Department of Education of Hubei Province

关键词 INSULIN dehydrocholic acid dehydrocholyl insulin chemical modification. Insulin, dehydrocholic acid, dehydrocholyl insulin, chemical modification.

分类号 O629.23 [理学—有机化学]

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Chinese Chemical Letters

2005年第6期

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Preparation and Analysis of Acylated Insulin with Dehydrocholic Acid

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