鸡传染性法氏囊病油乳剂灭活苗研究——Ⅱ.雏鸡接种油乳剂灭活苗后抗体消长规律及免疫细胞形态学

Studies on Oil-Emulsion Inactivated Vaccine against Infectious Bursal Disease (IBD)—— Ⅱ. Antibody Developments and Immunocytomorphology of the Oil-Emulsion Inactivated Vaccine against IBD

非免来航雏鸡接种IBD油乳剂灭活苗后15天,可达到具有保护力的沉淀抗体效价(GMT6.8～8),抗体高峰持续期为60天,疫苗免疫保护期为180天;免疫细胞的变化规律与抗体变化规律相似,但免疫细胞的变化早于抗体的变化,说明该疫苗具有良好的免疫原性。

Leghorn chickens free from IBD maternal antibody were vaccinated with the oil-emulsion inactivated vaccine against IBD. Antibody titer and number of lymphocytes in the vaccinated chickens were examined. The results indicated that the serum antibody titers increased to 6. 8-8 (AGPT) at 15 days post vaccination, and high antibody levels kept for 60 days and the effective preventive period was 180 days. The changes of lymphocyte number were similar to that of the serum antibody titers, but the increase of lymphocyte was earlier. These findings showed that the potency of the vaccine was better.