171例药品不良反应报告分析

Analysis of adverse drug reactions in 171 cases

目的分析引起不良反应药品的临床表现及防治。方法回顾性调查分析2004年西苑医院记录的171 例不良反应病例情况。结果 171例不良反应中,涉及中药注射剂71例(20种),占41.5％;抗生素共56例 (19种),占32．7％。静脉给药引起的不良反应146例, 占85．38％。提示临床医生在使用中药注射剂及抗生素,特别是静脉给药时,要严密监测,有不良反应征兆时及时处理,以免发生更严重的不良反应。结论中药注射剂、抗生素,尤其是静脉用药可能引起严重的不良反应,临床需要给予足够重视。

Objective To analyse the clinical representation and management of adverse drug reaction(ADR). Method 171 ADR cases of all Xi Yuan hospital inpatients reported in 2004 were analyzed retrospectively. Results In 171 ADR cases, 71 cases(20 types) accounting for 41.5% relate to traditional Chinese medicine injections,56 cases(19 types) accounting for 36.7% relate to antibiotics; in all 171 ADR cases ,146 cases(85.38%) are due to intravenous injections. More attention should be paid to traditional Chinese medicine injections and antibiotics, especially for intravenous injection.When signs of ADR emerged, related management must be carried out to avoid severe ADR. Conclusion ADR can be caused by many drugs,most of them are related to traditional Chinese medicines and antibiotics, severe reactions can be caused particularly by injections of these drugs.