摘要
测定了58例非胰岛素依赖型糖尿病(NIDDM)病人及48例正常人的血浆Lp(a)、ApoA1和ApoB浓度。NIDDM并发大血管病变组与无血管病变组比较,Lp(a)浓度升高,差异极显著,ApoB升高显著(P<0.05),ApoA1降低显著(P<0.01)。血浆Lp(a)与ApoA1、ApoB无显著相关性。提示Lp(a)、ApoA1、ApoB异常都是NIDDM大血管病变的危险因素之一。
he levels of plasma lipoprotein(a) Lp(a) ,apolipoprotein A1(ApoA1), apolipoprotein B(ApoB),were measured in 48 healthy subjects and 58 NIDDM patients including 29 cases with macroangiopathyand 29 without it.The levels of plasma Lp(a),ApoB in NIDDM patients with macroangiopathy wereall signiricantly higher than those in the patients without it,the level of ApoA1 was significantly lower,but the level of Lp(a) was even higher. There was no remarkable correlation between the level of plas-ma Lp(a)and the levels of plasma ApoA1,ApoB in NIDDM patients. The results suggested that thehigh Lp(a)level was of closer relationship to the incidence of NIDDM macroangiopathy than the levelsof ApoA1,ApoB. Lp(a)is an independent risk factor for NIDDM madcroangiopathy.
出处
《中国医科大学学报》
CSCD
1994年第4期365-367,共3页
Journal of China Medical University