摘要
根据黄酮类化合物抑制血小板聚集的机制和结构－活性关系，设计了五个７－乙酰水杨酰氧基黄酮衍生物，并由Ｂ环带不同取代基的７－羧基黄酮与乙酰水杨酰氯反应成酯而制得，其抑制血小板聚集活性正在研究中。
According to the mechanism of the inhibiting action of flavonoids on platelet aggregation and the structure-activity relationship.derivatives were designed and prepared form 7-hydroxyflavone with different groups on B-ring and acetylsalicylic acid.The study of the inhibiting action of those compounds on platelet aggregation is undergoing.
出处
《中国药物化学杂志》
CAS
CSCD
1994年第1期36-40,共5页
Chinese Journal of Medicinal Chemistry
关键词
羟基黄酮
合成
衍生物
乙酰水杨酸
Hydroxyflavone derivatives
Acetylsalicylic acid derivatives
