消痰平喘胶囊体外抑菌效果研究

The study of the inhibiting effects of the capsule of Eliminating Sputum and Relie-ving Asthma on bacteria in vitro

目的探讨消痰平喘胶囊对引起上呼吸道感染的致病菌抑菌效果。方法按照新药临床指导原则的要求,采用2倍稀释法测定消痰平喘胶囊对试验菌株的最小抑菌浓度(MIC)。结果消痰平喘胶囊对金黄色葡萄球菌、甲型溶血性链球菌、乙型溶血性链球菌、肺炎球菌和流感嗜血杆菌MIC50和MIC90分别为0.375～1.5mg/ml、0.75～3.0mg/ml。结论消痰平喘胶囊对引起呼吸道感染的常见致病菌具有较强的抑制作用。

Objective To study the inhibiting effects of the capsule of Eliminating Sputum and Relieving Asthma on pathogens which might cause the upper respiratory tract in vitro.Methods As was demanded by the practicing principles of clinical new medicines,twofold-dilution method was used to detect the MIC of the capsule of Eliminating Sputum and Relieving Asthma on tested strains.Results The MIC_~50 and MIC_~90 of the capsule of Eliminating Sputum and Relieving Asthma to Staphylococcus aureus,Streptolysin A,Streptolysin B,Pneumococcus,Hemophilus influenza were 0.375～1.5 mg/ml and 0.75～3.0 mg/ml respectively.Conclusion The capsule of Eliminating Sputum and Relieving Asthma had rather strong inhibiting effects on common pathogens.