米非司酮配伍米索前列醇中期引产的临床观察

Clinical treatment with mifepristone cooperating with misoprotol end mid-term pregnancy

目的:研究米非司酮配伍米索前列醇中期引产的临床效果.方法:16～27周妊娠要求引产妇女270例,其中研究组米非司酮配伍米索前列醇120例,对照组水囊宫腔置入结合催产素静点150例.结果:研究组与对照组24h内引产成功率分别为97.5%、80%(P＜0.01);48h内引产成功率分别为99.17%、92%(P＜0.05).结论:16～27周妊娠中期引产,米非司酮配伍米索前列醇效果优于水囊引产.

Objective:To study the clinical application of mifepristone cooperating with misoprotol to end mid-term pregnancy.Methods:270 cases of pregnant women,ranging from 16 to 27 weeks,are divided into a treatment group,120 cases treated by mifepristone cooperating with misoprotol,and a control group,150 cases with water-cyst placed into uterus.Results:Successful abortion rate within 24 hours is significantly higher in treatment group (97.5%) compared with that in control group (80%) (P<0.01);Successful abortion rate within 48 hours is significantly higher in treatment group (99.17%) compared with that in control group (92%) (P<0.05).Conclusion:The clinical application of mifepristone cooperating with misoprotol to end mid-term pregnancy produces more curative effects than that of water-cyst.