蛇床子超临界萃取物止痒作用的实验研究

Experimental Study on the Antipruritic Effect of Supercritical Fluid Extract of Fructus Cnidii

目的:考察蛇床子超临界萃取物外用的止痒作用。方法:以不同浓度的蛇床子超临界萃取物局部外用,观察其对磷酸组织胺致痒反应的影响。结果:蛇床子超临界萃取物局部外用可显著提高磷酸组织胺对豚鼠的致痒阈。结论:蛇床子超临界萃取物具有显著的止痒作用。

Objective:To define antipruritic effect of supercritical fluid ext ra ct (SFE) of fructus cnidii.Methods:The antipruritic effect on histamine acid pho sphate was observed through local application of SFE.Results:Regionally outuse o f SPE may obviously improve histamine acid phosphate inducing itch on guinea pig ′ s skin.Conclusion:SFE is obviously antipruritic.