氟哌酸耳用滴丸的研制及临床观察

The preparation and clinical effects of norfloxacin otic pills

本文介绍了氟哌酸耳用滴丸的处方、制备方法、质量控制标准及临床疗效观察。本品治疗急慢性化脓性中耳炎３６５例，总有效率达９８．６３％，具有局部用药浓度高、作用持久、用药次数少、不流淌、携带方便等优点，是治疗耳科疾病较理想的新剂型。

The method of preparation,standard of quality control andclinical effect of nor-floxacin otic pills(NP) were studied. 365 patients with acute and chronic purulent otitis mediawre treated with NP. It was effective in 98. 65%of the patinets. The advantages of these pills in-cluded high local concentration,prolonged effect no shedding etc, NP is ideal for the treatment ofotic diseases.