住院肺结核患者并发肺炎克雷伯氏菌感染26例临床分析

Clinical Analysis of 26 Pulmonary Tuberculosis In-patients Infected with Klebsiella Pneumoniae

目的探讨肺结核患者合并肺炎克雷伯氏菌感染的临床特点,提高对其发病、临床表现、预后的重视及诊治水平.方法对1994年1月～2003年11月间在我院住院并有两次以上痰培养结果为肺炎克雷伯氏菌感染的26例结核患者,进行回顾性临床分析.结果发现其具有临床表现不典型、常用抗菌药物敏感率较低,对氨苄青、头孢唑啉等耐药率较高的特点.经选用敏感抗菌药物及时合理治疗,预后较好.结论对肺结核患者并发肺内感染者应考虑到肺炎克雷伯氏菌感染,及时做痰细菌培养加药敏试验,合理选用抗菌药物也可取得较好疗效.

Objective To study the clinical characteristic of pulmonary tuberculosis [PTB] in-patients infected with klebsiella pneumoniae;To attach importance to their invasion,clinical manifesation and prognosis,and to improve competence of diagnosis and treatment. Methods 26 in-patients of PTB infected with klebsiella pneumoniae from January,1994 to November,2003, they were analyzed retrospectively, and whose sputum bacterial culture was klebsiella pneumoniae two or more times. Results Their clinical manifestations were not typical and not sensitive to the common antimicrobial. The occurrence rates of drug resistance to ampicillin,cefazolin was high. The prognosis was better by choosing sensitive antimicrobial and reasonable treatment in time. Conclusion When PTB patients had pulmonary infection,we should take into consideration to infection of klebsiella pneumoniae., make sputum bacterial culture,drug sensitirity test in time and reasonable choose sensitive antimicrobial.