回心草化学成分研究

Studies on the chemical constituents from herb of Rhodobryum roseum

目的:研究回心草的化学成分。方法:回心草95%乙醇提取物依次用石油醚、醋酸乙酯、正丁醇进行充分萃取,用硅胶柱色谱、葡聚糖凝胶柱色谱反复对醋酸乙酯部位进行成分分离、纯化,通过波谱方法鉴定结构。结果:从回心草中共分离鉴定了8个化合物,分别为胡椒碱(1),咖啡酸甲酯(2),尿嘧啶苷(3),熊果酸(4),3β-羟基-5α,8α-氧桥-6,22-二烯(5),3β-羟基-5α,8α-氧桥-6,9(11),22-三烯(6),β-谷甾醇(7),胡萝卜苷(8)。结论:化合物1-6和8为首次从该植物分离得到。

Objective: To study the chemical constituents from herb of Rhodobryum roseum. Method: The compounds were isolated by column chromatography, and identified by IR, NMR data. Result: 8 compounds were isokted and identified. They are piperine (1) , caf-feic acid methyl ester (2), uracil glucoside (3), ursolic acid (4), 5α, 8α-epidioxy-methylcholesta-6,22-dien-3β-ol (5), 5α, 8α-epidioxy-methylcholesta-6,9(11), 22-trien-3β-ol (6), β-sitosterol (7), daucosterol (8). Conclusion: 7 compounds (1-6,8) were isolated from this plant for the first time.