正常新生儿、婴幼儿胃及食管压力测定

Manometric Study of Stomach and Esophagus of Normal Neonates and Infants

对１８０例正常新生儿、婴幼儿进行胃、食管测压，结果得出不同年龄组胃、食管内压及食管、食管上、下端括约肌（ＵＥＳ，ＬＥＳ）高压区长度的正常值，同时发现随着年龄增长，ＬＥＳ、ＵＥＳ压力逐渐降低，而食管及ＬＥＳ、ＵＥＳ高压区长度逐渐延长，在１～２月ＬＥＳ的长度较食管的长度增长明显快。ＬＥＳ压力动态观察在２个月以内的小儿压力波形不稳定，出现明显上下波动，２个月后开始平稳；胃食管返流诱发试验有３例２～３天新生儿出现阳性，占２个月以内的８．３％，２个月以上３０例小儿中无阳性；ＬＥＳ长度在１～２月之间增长最快。这些提示ＬＥＳ功能成熟在生后２个月。

e performed gastric and esophageal manometry of 180 normal neonates and infants. We obtained the normal value of intraesophageal pressure and the length of high pressure zone of esophagus, LES,UES.We also found that the pressure of LES and UES gradually decreased with the increase in age while the length of high pressure zone of esophagus , LES and UES was gradually elongated.During 1 ─2 month age the length of LESL was significantly fast compared to that of esophagus. On making dy-namic observation of LESP the wave pattern of the pressure in infants under 2 months age was unstable and flaxation of the wave was very common,but after 2 months age began to be uniform. In 3 cases of 2─3 days old newborn GER inducing test were(+),about 8.3% of the newborn under 2 months age. In 30 cases of the infants above 2 months age the GER inducing test was negative. The growth af LES was most rapid during lst to 2nd month age.All of the above phenomenon suggest that the LES func-tion becomes matured after 2 month from birth.