大鼠下丘脑腹内侧核等核团内胆囊收缩素能神经元与儿茶酚胺系之间关系的免疫电镜观察

Immunohistochem-electron Microscope Study on the Relationship Between the Cholecystokinergic and Catecholaminergic Neurons in the Hypothalamic Ventromedial Nucleus in the Rats

以免疫电镜技术与人工伪介质小泡显示方法结合在一起，定性、定位地证明了大鼠下丘脑摄食中枢区域：下丘脑腹内侧核（ＶＭＨ）和下丘脑外侧区（ＬＨＡ）内分布的胆囊收缩素（ＣＣＫ）能神经元与儿茶酚胺（ＣＡ）能神经终末之间的超微结构关系，即突触的存在。否定了上述核团内ＣＣＫ与ＣＡ在同一神经元内的共存，为揭示下丘脑的摄食调节机理提供形态学依据。

The distribution and ultrastructural relationship(synapses)between the cholecystokinergic andcatecholaminergic neurons in the nucleus ventromedialis and lateral hypothalamic area of rat brain wereexamined with immunohistochem-electromicroscopic technique combined false transmitter small vesi- cles。In VMH and LHA area,there are feeding center,and there are ultrastructural relationships be-tween CCK neuron and CA nerve endings in above areas,ie between CCK neuron and CA nerve endingformed synaptic connection;It is illustrated that the CCK and CA neurons are not existed in the sameneuron at VMH and HLA area.This result provided the morphological bases for revealing mechanismof feeding regulation function。