摘要
为了解听觉脑干植入的特点，建立了耳蜗核急性电刺激动物模型。利用脑立体定位技术将铂铱合金双电极植入豚鼠耳蜗背核，施以双相脉冲电刺激，在大脑皮层听区记录中潜伏期反应，得到一组ＡＢＣ三相波。该波形与声刺激诱发者相似，潜伏期、波间期和动态范围存在一定差异，可证实为是听性反应。此外，对脑干电刺激的安全性问题也进行了讨论。
In order to examhe the Characteristics of the auditory brainstem implant,an animal model with electrical stimulation of the cochlear nucleus in guinea pigs was created.Middle latency response(MLR)to pulsatile electrical stimulation of the cochlear nucleus was recorded from the auditory cortex with bipolar plantinumiridium electrodes and stereotaxic technique.The electrically and acoustically generated MLRs have a similar morphology though there are little differences in the latencies,wave intervals and dynamic ranges.The results indicated that the central auditory pathways can be activated by means of electrical stimulation.The safety of the brain tissue to the electrical stimulation are also discussed.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
1994年第6期416-419,共4页
Acta Academiae Medicinae Sinicae
基金
国家自然科学基金
关键词
听觉脑干植入
中潜伏期反应
耳蜗核
电刺激
auditory brainstem implant
middle latency response
cochlear nucleus
electrical stimulation
