摘要
本实验从雷公藤多甙中又分离出3个三萜类化合物T_(16)、T_(17)、T_(18)经光谱数据分析和制备已知化合物的衍生物,确定了它们的分子结构,即T_(16)是salaspermicacid,T_(17)为雷公藤内酯乙(wilforlideB),T_(18)是一个新的齐墩果烯类三萜酸化合物,命名为雷藤三萜酮酸A(triptotriter-penonicacidA),化学名3-oxo-22(-hydroxy-△ ̄(12)-oleanen-29-oicacid。
Three more triterpenoids were isolated from total glucosides of tripterygium wilfordii(TⅡ).T16 and T17 were identified as salaspermic acid and as wilforlide B.T18 was a new compound.The structure of T18 was determined,as 3-oxo-22)α-hydroxy-△ 12-oleanen-29-oic acid by detail spectroscopic and chemical analysis,and named triptotriterpenonic acid A.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
1994年第6期466-468,共3页
Acta Academiae Medicinae Sinicae
关键词
雷公藤
雷公藤内脂
雷公藤内酯酮酸
tripterygium wilfordii hook f
salaspermic acid
triptotriterpenonic acid