银屑病辨证分型与红细胞变形能力及膜ATP酶活性的关系

Correlation between Syndrome Differentiation-Typing and Erythrocyte Deformability and Membrane ATPase Activity in Psoriatic Patients

本文报告３２例不同证型银屑病患者及３０例健康对照者红细胞变形能力及膜ＡＴＰ酶活性的检测结果。银屑病患者红细胞变形能力下降，Ｎａ＋－Ｋ＋－ＡＴＰ酶活性增高而Ｃａ２＋－Ｍｇ２＋－ＡＴＰ酶活性降低。异常的程度依次是血瘀型＞血燥型＞血热型。提示银屑病的确具有血瘀证指征，为本病的辨证分型提供了客观资料。

Erythrocyte deformability and membrane adenosine triphosphatase(ATPase) activity from 32psoriatic patients with TCM Syndrome Differentiation-Typing and 30 healthy subjects were observed.The results showed that in Psoriatic patients erythrocyte deformability reduced, and Na+-K++ATPase activity elevated while Ca++-Mg++ ATPase activity decreased.The degree of abnormality was in following order: the group of Blood Stasis(血瘀)>the group of Blood Dryness(血瘀)>the group of Blood Heat(血瘀),which suggested that there was definitely the sign of Blood Stasis in psoriatic patients.It might be considered as objective index for TCM Syndrome Differentiation and Taping of psoriasis.To guide the treatment of TCM and study the pathogenesis of psoriasis is important.