麒麟竭胶囊治疗多种出血的临床和实验研究

Clinical and Experimental Research on Various Bleedings Treated with Qi-Lin-Jie Capsule

对217例血证病人,用中药麒麟竭胶囊治疗175例,西药对照组42例。治疗结果中药组痊愈152例(止血天数3.197±1.2),显效5例,有效4例,无效14例;对照组分别为28例(止血天数3.910±1.7)、3例、5例、6例。显效率中药组为89.71％,对照组为73.8％,两组有显著差异(P<0.01);总疗效亦差异显著(p<0.05)。动物实验能显著缩短BT、CT、PT、KPTT而不促进血小板血栓形成。提示其止血与激活内源、外源凝血系统及影响血管舒缩功能相关。临床及动物毒性试验无明显毒付作用。

217 cases of bleeding syndrome were treated, in which 175 cases were treated with Qi-Lin-Jie capsule (group of TCM) and 42 cases with western medicine (control group). Results: in group of TCM, 152 cases were cured, 5 cases obvious effect, 4 cases effect and 14 cases no effect; in control group, it was 28, 3, 5 and 6 cases respectively. By animal experiment, it showed that the capsule could obviously shorten BT, CT, PT and KPTT but did not promote the formation of platelet thrombus. It suggests that its hemostatic effect be relative to activating endogenous and exogenous blood coagulation system and to influencing diastolization function of blood vessels. It had no obvious toxic and side effects by means of clinical and animal toxic tests.