单味大黄治疗急性胰腺炎(水肿型)的研究

Research on Acute Pancreatitis (Edematous Type) Treated with Single Rhubarb

本文以“六腑以通为用”理论为依据,对428例急性胰腺炎(水肿型)患者采用单味大黄治疗,并以复方西药组作对照,结果大黄治疗组显效率达83.2％,且在腹痛消失、退热、尿淀粉酶恢复正常时间方面优于复方西药组。随机对照比较证明大黄治疗急性胰腺炎的疗效与剂型无关。基础研究表明,大黄对胰腺细胞具有保护作用,并能改善微循环,抑制厌氧杆菌,降低血浆内毒素水平,是其治疗急性胰腺炎的主要机理所在。

Depending upon the theoretical basis that' the six fu-viscera function well when unobstructed' , 428 cases of acute pancreatitis (edematous type) were treated with single rhubarb. Control group was treated with compound western drugs. The results shown that,in the treatment group , the obvious effective rate was 83. 2% ,and the time of disappearence of abdominal pain,abatement of fever, recovery of amylase in urine was shorter than that in the control group. By means of random comparison, it proved that the curative effect of rhubarb on acute pancreatitis had no relation to the dose form. The basic research expressed that rhubarb had thd safety action on pancreatic cells and could improvemicrocirculation, inhibit anaerbic bacillus, and lower the level of plasma endotoxin, which were the main mechanisms of rhubarb in treatment of acute pancreatitis.