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BMPRI-B基因及其突变对绵羊排卵率的影响 被引量：3

Bone morphogenetic protein receptor IB and effects of its mutation on sheep ovulation
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摘要 近年来发现骨形态发生蛋白受体Ⅰ型基因(BonemorphogeneticproteinreceptorIB, BMPR IB) 突变和Booroola羊多羔表型完全一致, 从而认定BMPR IB基因为控制绵羊多胎性状的主效基因。本文从BMPR类型和信号传导机制及突变体对排卵率的影响等方面详述了BMPR的研究进展,旨在为研究和进一步利用该多胎基因提供参考。
作者 管峰 杨利国 艾君涛
机构地区 南京农业大学动物繁育研究所 华中农业大学动物科技学院
出处 《畜牧与兽医》 北大核心 2005年第3期48-50,共3页 Animal Husbandry & Veterinary Medicine
基金 上海市科技兴农重点攻关项目 农科攻字 ( 2002 ) 第1 3 6号
关键词 骨形态发生蛋白受体 绵羊 信号传导 排卵
分类号 S826.3 [农业科学—畜牧学]
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参考文献18

  • 1Shimasaki S, Zachow R J, Li D, et al. A functional bone morphogenetic protein system in the ovary[J]. Proceeding of the National Academy of Science USA, 1999,96:7282-7287.
  • 2张文岚,孙文伟,卜丽莎,李广生.Smad蛋白家族与骨形态发生蛋白信号传导[J].中国地方病学杂志,2002,21(4):325-327. 被引量：8
  • 3Wilson T, Wu X Y, Juengel J L, et al. Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK- 6) that is expressed in both oocytes and granulosa cells[J]. Biology of Reproduction, 2001,64:1225-1235.
  • 4管峰,杨利国,程瑞禾,曹少先.骨形态发生蛋白家族及其受体在生殖调控中的作用[J].生理科学进展,2004,35(3):262-264. 被引量：12
  • 5陈棣,叶伟胜,蔡芳.骨形态发生蛋白的受体及其信号传递过程[J].生物化学与生物物理进展,1999,26(2):141-143. 被引量：3
  • 6孙大业 郭艳林 马力耕.细胞信号传导[M](第3版)[M].北京:科学出版社,2001..
  • 7Attisano L, Wrana J L, Montalvo E, et al. Activation of signaling by the activin receptor complex[J]. Mol Cell Biol, 1996,16:1066-1073.
  • 8Hoodless P A, Haerry T, Abdollah S, et al. MADRI, a MAD-related protein that functions in BMP-2 signaling pathways[J]. Cell, 1996,85:489-500.
  • 9Nishimura R, Kato Y, Chen D, et al. Partnership between DPC4 and SMAD proteins in TGF-β signaling pathways[J]. Nature, 1996,383:832-836.
  • 10Souza C J H, Campbell B K, McNeilly A S, et al. Effect of bone morphogenetic protein 2 (BMP2) on oestradiol and inhibin A production by sheep granulose cells, and localization of BMP receptors in the ovary by immunohistochemistry[J]. Reproduction, 2002,123:363-369.

二级参考文献31

  • 1山西农业大学.养羊学[M]：第2版[M].北京：农业出版社,1993..
  • 2Wilson T, Wu X Y, Juengel J L, Ross I K, Lumsden J M, Lord E A,Dodds K G,Walling G A, McEwan J C, O' Connell A R, McNatty K P, Montgomery G W. Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells. Biol Reprod,2001,64(4) : 1225 ~ 1235.
  • 3Souza C J, MacDougall C, Campbell B K, McNeilly A S, Baird D'T.The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic receptor type 1 B (BMPR1B) gene. J Endocrinol,2001,169(2) : 1 ~ 6.
  • 4Mulsant P, Lecerf F, Fabre S, Schibler L, Monget P, Lanneluc I, Pisselet C, Riquet J, Monniaux D, Callebaut I. Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Merino ewes. Proc Natl Acad Sci USA, 2001,98 ( 9 ) :5104 - 5109.
  • 5Galloway S M, McNatty K P, Cambridge L M, Laitinen M P, Juengel JL,Jokiranta T S, McLaren R J, Luiro K, Dodds K G, Montgomery GW, Beattie A E, Davis G H, Ritvos O. Mutations in an oocyte-derived growth differentiation factor gene (BMP15) cause increased ovulationrate and infertility in a dosage-sensitive manner. Nature Genetics,2000,25:279 - 283.
  • 6Sambrook J, Fritsch E F, Maniatis T. Molecular Cloning. Second edition. New York : Cold Spring Harbor, 1989,463 - 469.
  • 7WANG Ai-Hua. Molecular cloning of BMP15, BMPR-IB and SSCP analysis of LHβ gene in pig[Thesis for Doctoral Dissertation]. Beijing : Agricultural University of China, 2002.
  • 8DU Li-Xin,CAO Ding-Guo,JIANG Yun-Liang. Study on DNA markers of microsatellites and RAPD for Little Tailed Han Sheep. Proceedings of 11th National Symposium on Animal Genetics and Breeding.Beijing:Agricultural Science and Technology of China Press, 2001,96 - 99.
  • 9Davis G H, McEwan J C, Fennessy P F, Dodds AgResearch K G. Discovery of the lnverdale gene ( FecX). Proceedings of the New Zealand Society of Animal Production. Invermay Agricultural Centre, Private Bag, Mosgiel, New Zealand, 1995,55 : 289 - 290.
  • 10Davis G H, McEwan J C, Fennessy P F. Infertility due to bilateral ovarian hypoplasia in sheep homozygous ( FecX1 FecX1) for the Inverdale prolificacy gene located on the X chromosome. Biology of Reproduction, 1992,46 : 636 - 640.

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畜牧与兽医
2005年 第3期

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