实验恒河猴超声心动图的初步研究

Echocardiography of Rhesus Monkeys(Macaca mulatta)

分别采用二维、脉冲多普勒及M型超声心动图Teichholtz公式对1 0只健康成年实验恒河猴(Macacamulatta)的心脏结构、心脏血流动力学及左室收缩功能进行测定,并比较不同性别间各参数的差异,以建立正常健康成年恒河猴超声心动图相关生理学参数的基础正常值。结果表明,健康成年实验恒河猴超声心动图各项生理指标类似于人类新生儿的指标,雌、雄组间比较除室间隔舒张末期厚度有统计学差异外(P <0 0 5 ) ,其余指标均无统计学差异(P >0 0 5 )。

Ten healthy adults Macaca mulatta were tested separately by 2-dimensional(2D),pulsed Doppler and M-mode echocardiography to determine the normal value of echocardiography for healthy M. mulatta.The 2DE-related indexes,cardiac hemodynamic variables and left ventricular systolic function were measured,and all the indexes were compared between both sexes.The results showed that all the indexes above M. mulatta were similar to those of human newborns.Except a statistical difference in interventricular thickness in diastole (P<0.05) between the male and female,the other indexes were not statistically different.